Moreover, the Ku80+ cells in these LGGs also expressed CD133 and ABCG1 (Fig. 1d), markers of glioma stem cells [15, 59], but were immunonegative for SOX10 and p16 expression, which can be observed in some patient pediatric LGGs (Fig. 1d). The gene discussed is XRCC5; the disease is central nervous system cancer.