A number of blood and urinary biomarkers have been shown to predict the development of AKI, such as plasma or urinary neutrophil gelatinase-associated lipocalin (NGAL), urinary kidney injury molecule 1 (KIM-1), urinary tissue inhibitor of metalloproteinase-2 (TIMP-2), and insulin-like growth factor-binding protein 7 (IGFBP7), and others [31]. The gene discussed is TIMP2; the disease is acute kidney injury.