An additional year of age was associated with a 8% increased risk of death, and an over threefold increase for procalcitonin≥0.2 ng/mL, D-dimer≥1.04 mg/L, ESRD, saturation < 96%, CVD, CRP ≥ 43 mg/L and COPD. The gene discussed is CRP; the disease is chronic obstructive pulmonary disease.