While not the focus of this study, other potential links between SP140 and cancer were observed, including high expression of SP140 in chronic lymphocytic leukemia patients’ cells (although reduced expression in acute myelogenous leukemia), and high binding of SP140 to the FLOT1 gene, which has been implicated in tumorigenesis [36]. The gene discussed is FLOT1; the disease is B-cell chronic lymphocytic leukemia.