GH1 and bipolar disorder: In a secondary analysis, comparing only patients with bipolar disorder type 1 and controls, GH was again the only protein with a significant association between CSF concentrations and bipolar disorder in both cohorts, and with larger effect sizes than in the analysis including all patients (SBP-S: β = −0.56, p = 0.046; SBP-G: β = −1.75, p < 0.001, see Supplementary table 4).