In another context, such a shift is extensively observed in neonates who are susceptible to pathogens and at risk to develop allergic reactions.32 One approach to explaining the etiology of SIDS is the allergy to bacterial toxins: It is speculated that non-antibody-regulated induction of mast cell degranulation, leading to anaphylaxis, is activated in SIDS via increased IFN-γ induced by pyrogenic staphylococcal toxins.7 However, we did not find elevated IFN-γ concentrations in SIDS lungs. The gene discussed is IFNG; the disease is Allergy.