We found that whilst the proportion of c-Kit+ MDSCs was similar in small (treated) and large (control) tumours (Fig. 3a, b), there was a reduction in the absolute number of c-Kit+ PMN-MDSCs and M-MDSCs, corresponding with fewer overall MDSCs in the spleen (Figs. 1e, f and  3c, d). Here, KIT is linked to neoplasm.