Therefore, we sought to test whether the effects of basophils on gametocytemia and transmission could be attributed to basophil IL-18R To the contrary, however, the percentage of infected mosquitoes was reduced in mosquitoes that fed on basoIL-18R (−) mice relative to those that fed on basoIL-18R (+) mice (Fig. 7A), but there was no difference in infection intensity (oocysts per midgut) in mosquitoes that fed on mice with these genotypes (Fig. 7B). This evidence concerns the gene IL18R1 and infection.