In contrast, some of the low frequency fusions, CCDC6-RET in thyroid and NSCLC lung cancer, FGFR2-BICC1 in cholangiocarcinoma, PTPRZ1-MET and KIF5B-RET in non-small cell lung (NSCLC) cancer (≤5 fusions detected) did show linkage to tumour type (Fig 1 and S6–S8 Tables). This evidence concerns the gene PTPRZ1 and cholangiocarcinoma.