Since obesity per se is a known driver of gut dysbiosis and impaired immune response to antigens, it may explain why we found no differences between the two groups.19,20 However, there was a positive correlation between HbA1c levels and systemic IgG as well as IgA against E. cloacae (Figure 1e), particularly in people with T2D. The gene discussed is CD79A; the disease is Obesity.