In our study, we investigated the expression status of several tumor markers, which are commonly used in the current clinic.[31] Patients with GC in the lesser curvature had higher levels of EGFR expression compared with those with GC in the larger curvature; in addition, the 5-year survival in EGFR-negative group was significantly higher than that in the EGFR-positive group. This evidence concerns the gene EGFR and neoplasm.