Although the exact pathogenesis is still unelucidated, the increased proportion of circulating CD4+ T cells, CD8+ T cells, and neutralizing antibodies is thought to have differing roles.[15] Vaccination-related nephrotic injury associated with the administration of other vaccines,[16] such as for influenza, hepatitis B, pneumococcus, and measles, has also been reported; MCD and acute kidney injury occurred more frequently, while IgAN was less common. This evidence concerns the gene CD8A and acute kidney injury.