In addition, an unvaccinated patient with a moderate COVID-19 subtype exhibited a mild increase in IL-10, TNF-α, and IL-12 p70 on day 12 of hospitalization; however, a vaccinated patient with moderate COVID-19 displayed relatively high IL-2 and TNF-α on day 15, suggesting that vaccinated patients with COVID-19 are more likely to stimulate an immune response. The gene discussed is TNF; the disease is COVID-19.