After treatment, NIHSS score, cerebral infarct volume, NSE, and S100β levels were reduced compared with those before treatment in this group, and NIHSS score, cerebral infarct volume, NSE, and S100β levels in the observation group were lower than those in the comparison group after treatment, and the differences were statistically significant (P < 0.05). Here, ENO2 is linked to cerebral infarction.