For example, two patients with the same PTV in the DMD gene displayed different clinical phenotypes, with one diagnosed with Duchenne muscular dystrophy, and the other with the milder Becker muscular dystrophy; here, the difference in the phenotype was suspected to be caused by weaker NMD efficiency in the less severely affected patient, which resulted in the production of the damaged but still partially functional DMD protein (Kerr et al., 2001; Torella et al., 2020). Here, DMD is linked to Duchenne muscular dystrophy.