CGAS and neoplasm: Data from TCGA database revealed that the cGAS-STING score was significantly higher in BRCA, CESC, COAD, ESCA, HNSC, KIRC, KIRP, LUAD, READ, STAD, and THCA tumor tissues compared to that in paired normal tissues, suggesting that cGAS-STING might play oncogenic roles in the development of those tumor types (Figure 2).