Univariate logistic regression analysis showed four factors associated with MI in anti-MDA5 Ab+ DM/CADM patients, which included three risk factors containing dysphagia (OR 3.923, 95% CI 1.085, 14.181, p = 0.037), increased peripheral WBCs (OR 1.201, 95% CI 1.003, 1.438, p = 0.046), and NT-proBNP >600 pg/ml (OR 18.333, 95% CI 1.508, 222.875, p = 0.022), and one protective factor plasma ALB (OR 0.892, 95% CI 0.796, 0.999, p = 0.048) (Table 4). The gene discussed is NPPB; the disease is dermatomyositis.