ITGAM and neuropathy: In the sciatic nerve crush injury traumatic neuropathy model (54), we observed intense injured sciatic nerve CD11b+ CD45+ leukocyte infiltration in both male and female Gdnf WT and Gdnf CKO mice at the peak of axonal degeneration (day 7 post-injury) relative to the Sham surgery (uninjured) sciatic nerves in the same mice.