Instead, the LIAS expression was downregulated in most cancers, like breast invasive carcinoma (BRCA), colon adenocarcinoma (COAD), KIRC, kidney renal papillary cell carcinoma (KIRP), prostate adenocarcinoma (PRAD), rectum adenocarcinoma (READ), thyroid carcinoma (THCA), and uterine corpus endometrial carcinoma (UCEC) (Figure 1A). The gene discussed is LIAS; the disease is rectum adenocarcinoma.