The expression data of 29 m7G-related genes in 59 normal and 535 LUAD tissues were extracted from the TCGA database, and 12 DEGs that met the criteria (|log2FC| > 0.5 and FDR< 0.05) were identified: DCPS, EIF4E1B, EIF4E3, EIF4G3, LARP1, LSM1, METTL1, NCBP1, NCBP2, NCBP2L, NSUN2, and WDR4. Among these, EIF4E3 was downregulated, and all the others were upregulated in tumor specimens. The gene discussed is EIF4E1B; the disease is neoplasm.