CPNE8 and gastric cancer: To gain insight into the effects of CPNE8 on the cellular behavior of GC tumorigenesis, we generated the BGC823-oe-CPNE8 cell line, which stably overexpressed full-length CPNE8. We also developed an AGS-sh-CPNE8 cell line that stably expressed CPNE8-shRNA to suppress CPNE8 expression.