The results showed that the transcriptional activity of pGL3-37/+96 Del KLF4 was decreased to the basal level and the transcriptional activity of pGL3-37/+96 Mut KLF4 was dramatically decreased compared with its wild-type counterpart in four NSCLC cell lines tested (Figure 4D). This evidence concerns the gene KLF4 and non-small cell lung carcinoma.