Furthermore, significant correlations were detected between lncRNAs and IL-6, CCL2, TNF-α, and other diagnostic biomarkers that might explain the pathogenic role of NEAT1 and TUG1 in disease through targeting the production of these cytokines, drawing attention to the use of RNAi knockdown for lncRNAs under expression that may partially put off the cytokine storm in COVID-19 infection and preclude ARDS. The gene discussed is NEAT1; the disease is acute respiratory distress syndrome.