Moreover, the roc curve was established to distinguish between the moderate and severe COVID-19, and we found that IL-6 at the cutoff of 356.94 is an efficient determinant of severity with 100% (sensitivity, specificity, PPV, NPV, and accuracy P<0.001), followed by CCL2 at the cutoff of 46654.81 with a sensitivity of 91.1%, specificity of 82.9%, PPV of 87.2%, NPV of 87.9% and 87.5% accuracy P<0.001) and NEAT1 at the cutoff of 1481.008 with (68.9% sensitivity, 68.6% specificity, 73.8% PPV, 63.2% NPV, and 68.8.5% accuracy P=0.05). Here, NEAT1 is linked to COVID-19.