SERPING1 and acute kidney injury: To interrogate the relevance of SerpinG1 to the anti-septic AKI efficacy of high-dose ascorbate, mice were injected with AAV9-Ksp-GFP-shSerpinG1 (AAV9-sh.SerpinG1) or the control vector AAV9-Ksp-GFP-shScramble (AAV9-Scr) (Figure 7A).