BECN1 and obstructive sleep apnea syndrome: Intermittent hypoxia has previously been shown to induce autophagic activity in both animal models and in clinical contexts, with one study having observed elevated Beclin-1 protein levels in OSA patient serum as compared to patients without OSA, and these Beclin-1 levels were correlated with oxygen desaturation index and apnea-hypopnea index values for these patients (Schlemmer et al., 2021).