We then validated the expression of key genes in CM and normal skin using the Human Protein Atlas (HPA) database; however, because the HPA database lacked immunohistochemical images of normal and tumor tissues for CXCL10 and EMP3, we validated only the expression of the remaining three key genes, which were all significantly different (Fig. 13A–C). The gene discussed is CXCL10; the disease is neoplasm.