RUNX3 and cutaneous mastocytosis: In contrast, indicators such as RUNX3 (human runt-related transcription factor 3) [33] have a high degree of accuracy in predicting the prognosis of CM, and traditional inflammation-related serum biomarkers such as neutrophil ratio and lymphocyte/monocyte ratio have also performed well in predicting the prognosis of CM, but no report of inflammatory response-related gene models as prognostic markers of CM has been made.