In other words, the radiology specialists could observe the target lesion more clearly by distinguishing the boundary between prostate cancer and normal prostate by the anti-inflammatory effect of vitamin D. Although the relationship between the serum vitamin D levels and multiparametric MRI results needs to be validated in future studies, multiparametric MRI may be recommended for patients with slightly elevated PSA levels and elevated serum vitamin D levels. Here, KLK3 is linked to prostate cancer.