Although not statistically significant, the trend of higher [18F]FDG accumulation in HER2– tumor than in HER2+ tumor on a %ID/cm3 basis correlated with the higher growth rate of MD468 (HER2–) than of SKBR3 (HER2+) that we observed both in vitro and in vivo (Figs. 3B and 3D). Here, ERBB2 is linked to neoplasm.