CXCL8 (also known as IL-8) levels were found to be highly upregulated and significantly increased the Ca2+-dependent outflow of K+ in red blood cells in patients with hypertension [12] Moreover, CXCL5-CXCR2 signalling mediates lens injury-induced cell infiltration through AKT activation [13]. Here, CXCR2 is linked to hypertensive disorder.