Consequently, gene features which have a high node degree (90th percentile) and which are also significantly differentially expressed in DCM as compared to controls (P<0.05 FDR) were selected, which results in the following genes: ERC2, CCDC80, NEB, TXNRD1, COL14A1, TPM3, SYNPR, MAP1A. The gene discussed is TXNRD1; the disease is familial dilated cardiomyopathy.