CCL2 and melanoma: Bindarit efficiently inhibited MCP-1 secretion from melanoma- or SFM-activated human astrocytes and in LPS-stimulated murine astrocytes by 0.3- or 3- and 4-fold, respectively, whereas CM of melanoma cells (WM115 and D4M.3A) enhanced the basal secretion of MCP-1 by 3-fold (Figure 2D).