Indeed, MCP-1 was found to be a potent factor for melanoma migration in all the cell lines tested, including human primary and metastatic melanoma (WM115 and 151/4-5B1) and murine primary melanoma cell lines (D4M.3A and B16-F10) — 40% and 50% migration inhibition (Figure 1D and Supplemental Figure 7B). This evidence concerns the gene CCL2 and melanoma.