About TFEB-rearranged renal cell carcinomas, finally, a statistical correlation of relevant levels was reported with negative expression of CD10 (p = 0.0002 with a 5% cutoff and p = 0.0001 with both a 10% and a 20% cutoff), CA9 (p = 0.0002 with both a 5% and a 10% cutoff and p = 0.0001 with both a 20% cutoff), and CD13 (p = 0.0001) and with cathepsin K (p = 0.0001) and parvalbumin positivity (p = 0.0001 with a 5% threshold and p = 0.0048 with both a 10% and a 20% threshold), no matter what the cutoff used was. This evidence concerns the gene TFEB and hereditary clear cell renal cell carcinoma.