Importantly, IPF lungs showed higher percentages of SEMA7A positive fibroblasts compared to normal lungs by flow cytometry analysis on freshly isolated lung fibroblasts (Fig. S2 C and Fig. 2 K) and this might explain the increased migration and invasion of IPF lung fibroblasts when compared to normal fibroblasts. The gene discussed is SEMA7A; the disease is idiopathic interstitial pneumonia.