It was a pity that there was limited data on ALKBH family function in breast cancer, but we found that ALKBH family abnormal expression was associated with PI3K-AKt signaling pathway, Axon guidance, ECM-receptor interaction, protein digestion, and absorption, PPAR signaling pathway by performing functional annotation base on GO and GESA. The gene discussed is PPARA; the disease is breast carcinoma.