As previously described, the correlation analysis of the methylation levels between total analysed region of TERT promoter and UTSS region was acutely significant (Pearson r = .839, p < .0001) (Figure 2B), and tumours either with UTSS region or with a total promoter region methylation average superior to established threshold of 16.1% were considered TERT promoter methylated. The gene discussed is TERT; the disease is neoplasm.