Methylation of TERT promoter (methylation average of the 39 CpG sites within the −514‐ to −120‐bp region from ATG site >16.1%) and co‐existence of pathogenic events at TERT locus and gene expression were attributes mainly limited to short telomere tumours in differentiated carcinomas (Figure S5D and Figure 3A), suggesting that telomere shortening facilitates the occurrence of structural and transcriptional alterations related to TERT locus. This evidence concerns the gene TERT and carcinoma.