Regarding TERT promoter mutations, this event was significantly more frequent in clinically aggressive tumours (45.7%, 21/46) than in disease‐free tumours (3.4%, 2/58) (p < .0001, Fisher exact test), being the frequencies of c.‐124C>T (C228T) and c.‐146C>T (C250T)‐specific mutations 87% (20/23) and 13% (3/23), respectively. The gene discussed is TERT; the disease is neoplasm.