We tested the level of tumor cell oxidative stress after DLL treatment and found that DLL treatment significantly inhibited the expression of NADPH, SOD1, and GPX and the activity of SOD and GPx, promoted the level of ROS, and reduced the levels of NAD+/NADH and ATP compared with the control (Figures 5(d) and 5(e)). This evidence concerns the gene SOD1 and neoplasm.