IFNG and chronic myelogenous leukemia, BCR-ABL1 positive: On the other hand, BCL6 knockdown did not inhibit, while the presence of 10 μM A-1210477 completely counteracted the anti-apoptotic effect of IFNγ on imatinib-treated JURL-MK1 cells.13 We now show that although MCL-1L is upregulated by IFNγ in CML stem/progenitor cells, inhibition of MCL1 activity with 10 μM A-1210477 only partially counteract the anti-apoptotic effect of IFNγ in these cells.