Accordingly, the anti-apoptotic effect of IFNγ on JURL-MK1 cells was counteracted by the presence of the selective MCL1 inhibitor A-1210477, suggesting that IFNγ might exert its anti-apoptotic effect on CML cells through the upregulation of MCL-1L.13 This evidence concerns the gene MCL1 and chronic myelogenous leukemia, BCR-ABL1 positive.