IFNG and chronic myelogenous leukemia, BCR-ABL1 positive: However, the presence of A-1210477 only minimally inhibited the anti-apoptotic effect of IFNγ on imatinib treated CML stem/progenitor cells, and even the apoptosis induced by A-1210477 monotherapy was completely counteracted by IFNγ in these cells (Figure 6b).