Similar to the results obtained on JURL-MK1 cells, activated TCM markedly increased the number of viable (Figure 4a) and decreased the rate of apoptotic (active caspase-3/7 positive) (Figure 4b) CML stem/progenitor cells, both in the absence or presence of imatinib. Here, CASP3 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.