Through unbiased clustering analysis of high dimensional flow cytometry data, another study found three previously undescribed clusters of Tregs in this model (1) KLRG1+CD69+ Tregs described as terminally differentiated, tumor-infiltrating Tregs (2) FoxP3+CD25loLAG-3+ Tregs that were enriched in leukemic mice and represented a reservoir of suppressive Tregs (3) CD44loCD62L+CD38-KLRG1- Tregs that were not enriched in leukemic mice and represented naïve Tregs (91). This evidence concerns the gene KLRG1 and neoplasm.