In addition to elevated TGFB1 expression in COPD, the receptors with the highest predicted interaction potential score for TGFB1 (TGFBR1 and TGFBR2) exhibited also higher expression in monocyte-like macrophages from COPD patients (Figure 5F). This evidence concerns the gene TGFBR2 and chronic obstructive pulmonary disease.