In regulating T cell immunity: Low-dose curcumin treatment (0.1 and 1 μg/ml) was also shown to reduce Th17 cells, IL-17A levels, and increase Treg and TGF-β1 concentrations on CD4+ T cells in SLE patients compared with normal controls (111). The gene discussed is TGFB1; the disease is systemic lupus erythematosus.