To clarify CLEC5A mRNA expression in different cell types in pan-cancer, we obtained single-cell RNA sequencing data of BLCA, BRCA, CHOL, COAD, GBM, HNSCC, KIRC, LIHC, LUAD, OV, PAAD, SKCM, and STAD for analysis. This evidence concerns the gene CLEC5A and head and neck squamous cell carcinoma.