The results exhibited that the CLEC5A mRNA expression was mainly negatively correlated with its DNA methylation in most tumors but only positively correlated with its DNA methylation in only some tumors, such as SKCM (cutaneous skin melanoma), TGCT (testicular germ cell tumors), LIHC and HNSC (Figure 3B). This evidence concerns the gene CLEC5A and testicular germ cell tumor.