ACE2, AGT, CCL2, CCL3, CSF3, CXCL10, CXCL8, IL10, IL1B, IL2, IL2RA, IL6, TMPRSS2, and TNF were the genes related to the “COVID-19 adverse outcome pathway” [WP4891 with p = 3.27 × 10–11 and genes ratio of 93.3% (14/15)]. The gene discussed is ACE2; the disease is COVID-19.