NEAT1 and nasopharyngeal carcinoma: NEAT1 (nuclear paraspeckle assembly transcript 1) has also been associated with HNSCC chemoresistance, especially in NPC where its depletion repressed the cisplatin resistance of NPC cells and phenocopied the effect of miR-129 overexpression, which also enhanced apoptosis by the histone deacetylase inhibitor SAHA (122, 126).