NSUN2 and Familial prostate cancer: In addition, we analyzed the effect of NSUN2 on the IC50 of chemotherapy drugs for prostate cancer by using gene-drug response data from the GDSC database and found that NSUN2 had a significant effect on chemotherapy drugs commonly used in the clinical setting, including docetaxel, doxorubicin, fluorouracil, cisplatin, and etoposide.