MYO6 and colorectal carcinoma: Knockdown of circ_0000231 can inhibit glycolysis and the growth of CRC cells by sponging miR-502-5p, which binds to myosin VI (MYO6) (78). A recent published study has suggested that circPLCE1 could also function as a ceRNA binding with miR-485-5p and expedite epithelial mesenchymal transformation (EMT) and glycolysis of CRC cells (79).