LINC00525 is documented to activate HIF-1α, increase the expression of ubiquitin-conjugating enzyme E2Q family member 1 (UBE2Q1), and enhance hypoxia-enhanced glycolysis through miR-338-3p/UBE2Q1/β-catenin axis in CRC (46). The gene discussed is UBE2Q1; the disease is colorectal carcinoma.