Although high expression of CysLTR2 appears in resection tissues of HCC patients and in AAI-induced premalignant livers of canines, the data from both HepG2lv-FLAP and HepG2sh-FLAP cells do not demonstrate the impact of FLAP abundance on CysLTR2 expression. This evidence concerns the gene ALOX5AP and hepatocellular carcinoma.