Commonly mutated genes in lung adenocarcinoma in Eastern populations include EGFR (~60%), KRAS (~11%), and anaplastic lymphoma kinase (ALK; ~2%), and mutations have also been identified in MET (1%), HER2 (~2%), BRAF (~2%), RET (1%–4%), and ROS1 (~2%) (3, 4). This evidence concerns the gene ALK and lung adenocarcinoma.