Results of univariate analysis showed that NLR (p < 0.001), plasma LDH (p < 0.001), smoking (p < 0.009), RPILD (p < 0.001), dyspnea (p < 0.001) and HRCT score were associated with OS of MDA5 + DM patients (Table 2). Here, IFIH1 is linked to diabetes mellitus.