On the other hand, our results identified that the TRAF6 levels in CD19+CD27+ memory B cells were upregulated in GMG patients compared with OMG patients in the acute aggravation state and that there was a positive relationship between the TRAF6 level in the memory B cells of MG patients and MG-ADL scores, suggesting that overexpression of TRAF6 in memory B cells may predict disease severity in MG. Here, TRAF6 is linked to myasthenia gravis.