Then, we mainly focused on metabolism to simplify the interpretation of our results, conducted a heatmap analysis of metabolism‐related proteins with significantly different expression levels, and identified MTTP (Figure 4B), which was discovered as an intracellular lipid transfer protein.[50] The Kaplan–Meier survival curves and log rank test showed that high MTTP expression significantly correlated with shorter overall survival (OS) and disease‐free survival (DFS) of patients with colorectal cancer (Figure 4C), suggesting that MTTP represents a factor that promotes tumor progression in CRC. This evidence concerns the gene MT-TP and colorectal carcinoma.